Tag Archives: York

THYME Project Proof of Concept Scheme – Successful Projects Announced

The THYME project brings together researchers from the Universities of Hull, York and Teesside to address regional bioeconomy challenges. THYME have just announced the first projects to be awarded proof-of-concept funding with a total of £350,000 awarded to seven projects. A second round is expected later this year and THYME expects to run a three-year programme of Proof of Concept projects.

More details on the awards and how to apply can be found here

The projects funded are: Read more

FUJIFILM Diosynth Biotechnologies Centre of Excellence in Bioprocessing 2.0

FUJIFILM Diosynth Biotechnologies (Fujifilm), a leading Contract Development and Manufacturing Organization (CDMO) with experience in the development and manufacture of recombinant biopharmaceuticals and gene therapies, has announced the inception of the “FDB Centre of Excellence in Bioprocessing 2.0” (CEB) in the United Kingdom. This initiative is an extension of Fujifilm’s global innovation initiatives. Read more

Enhanced functionalisation of major facilitator superfamily transporters via fusion of C-terminal protein domains is both extensive and varied in bacteria

Benjamin J. Willson, Lindsey Dalzell, Liam N. M. Chapman, Gavin H. Thomas

The evolution of gene fusions that result in covalently linked protein domains is widespread in bacteria, where spatially coupling domain functionalities can have functional advantages in vivo.Fusions to integral membrane proteins are less widely studied but could provide routes to enhance membrane function in synthetic biology. Read more

CBMNet scientists identify key step in production of Body Odour

CBMNet-funded scientists from the Universities of York and Oxford, along with industrial partner Unilever, have unravelled a key part of the molecular process by which armpit bacteria produce the most pungent component of the noxious smell we recognise as BO. The findings could result in more effective deodorants with targeted active ingredients, the researchers suggest. Read more

13 New CBMNet Projects Funded

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13 New CBMNet Projects Funded

We are pleased to announce that we have recently funded 13 new projects in Industrial Biotechnology and Bioenergy. 

Proof-of-Concept Projects

  • Dr Neil Dixon, University of Manchester, CPI and Oxford Biotrans – Identification of Membrane Transporters of Lignin monomers
  • Professor David James, University of Sheffield and UCB Pharma – Engineering Exosome Production by CHO Cells
  • Professor Doug Kell, University of Manchester and Croda – A potent synthetic biology strategy for increasing transporter-mediated terpenoid efflux from E. coli

Business Interaction Vouchers

  • Dr Mark Shepherd, University of Kent and FujiFilm – Engineering E. coli for enhanced production of antibody fragments
  • Dr Mark Shepherd, University of Kent and FujiFilm – Lowering the disulphide load in the periplasm of E. coli cell factories
  • Dr Teuta Pilizota, University of Edinburgh and FujiFilm – Replacing osmotic downshocks with upshocks for periplasmic protein extraction

Vacation scholarships

  • Dr Frans Maathuis, University of York – The role of HMA and COPT proteins in trans membrane movement of palladium 
  • Professor Colin Robinson, University of Kent – An enhanced platform for translocation of biotherapeutics to the E. coli periplasm
  • Dr Alan Goddard, University of Lincoln – Modelling of multifactorial solvent stress on membranes
  • Dr Wuge Briscoe, University of Bristol – Bacterial mimicking liposomes
  • Dr Boyan Bonev, University of Nottingham – Membrane stability models in the presence of methacrylate esters
  • Dr Sam Miller, University of Aberdeen – Investigating the role of periplasmic and transmembrane domains of mechanosensitive channels in E.coli membrane integrity
  • Dr Claudio Avignone-Rossa, University of Surrey – Construction of glucose transporter mutants of Clostridium beijerinckii

You can view all our projects funded to date here and read our success stories here.

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