EARLY CAREER RESEARCHER GRANTS

We already funded several Early Career Researchers to attend conferences and events that have been highly successful.


Arthur Neuberger, University of Cambridge

We sponsored Arthur to present at the EFM Microbial Stress Meeting.

The meeting covered a broad range of original research talks on various mechanisms and effects of microbial stress responses. These were discussed in the context of clinical or industrial relevance. The organising committee did a fantastic job in selecting a rich variety of abstracts and invited speakers. Since most of these mechanisms involve some sort of cross-membrane transport of toxic substrates, this meeting was a very good fit for CBMNet.

My talk was one of several touching upon the role of multi-drug efflux pumps as key stress response mechanism to antibiotic stress and drivers of AMR. However, it was the only structural talk at this conference. I received positive feedback in two respects: In my talk, I covered (1) the functional and structural investigation of a clinically relevant efflux system (MacAB/TolC) and (2) a brief introduction into the application of cryo-EM for structural biology of membrane proteins. Various conference attendees approached me after my talk expressing interest in either the scientific content or the use of cryo-EM for their own project (or both).

To my positive surprise, one of the conference attendees was Dr. Gerd Seibold (we had met at the very first CBMNet meeting in Sheffield in 2014). During the meeting in Kinsale, we agreed to set up a collaboration project around his Corynebacterium glutamicum channel target. Gerd has functionally investigated the channel and proposed a two-conformational transition model which we both are hoping to confirm by solving its near-atomic structure in those two conformational states. Hence, beyond the interesting content of the meeting, I am happy to say that it also resulted in a potential collaboration.

Conference location (Kinsale) was a picturesque fishing town with a decent amount of tourist attractions and activities. Both conference venues/hotels (including catering) were of high quality. The atmosphere was friendly and open. Various coffee breaks and poster sessions allowed for fruitful discussions in between and after scientific sessions. All sponsors were gratefully acknowledged and advertised at the start and end of the meeting.

 


Arthur Neuberger, University of Cambridge

We sponsored Arthur to present a poster at the ‘Membrane Proteins from A to Z’ conference: Molecular Defence Mechanisms In Bullet-Proof Microbial Killers: On the role of multidrug resistance-causing efflux pumps in bacteria – and a tale of a hidden “Janus” amongst substrates for the multidrug efflux pump LmrP.

You can view his poster here.

”I would like to thank CBMNet for the great opportunity to attend and be part of this rather extraordinary meeting.”


Ibrahim Yaseen, University of Leeds

We sponsored Ibrahim to present a poster at the ‘Membrane Proteins from A to Z’ conference: Challenges in Tetraspanin Characterisation: Novel mAbs Against The Native Form of Tspan2.

You can view his poster here.

”I feel my attending and contribution to this symposium was successful, and it gave the opportunity to communicate and share knowledge with the academics and the attendees.”


Laurence Humphrey, ex-ReBio Technologies

We sponsored Laurence to attend our meeting on Membrane Transporters for IBBE.

You can read the report here.

”As a result of the CBMNet ECR grant I have new contacts at 4 industrial biotechnology organisations that may have career opportunities for me in the next 12 months.  The networking opportunities also gave me an opportunity to gain new perspectives on industrial biotechnology from different positions and companies in the UK as well as abroad.’’