Pseudomonas stutzeri as an alternative host for membrane proteins

Pseudomonas stutzeri as an alternative host for membrane proteins Background Studies on membrane proteins are often hampered by insufficient yields of the protein of interest. Several prokaryotic hosts have been tested for their applicability as production platform but still Escherichia coli by far is the one most commonly used. Nevertheless, it has been demonstrated that in some cases hosts other than E. coli are

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Government Publishes paper on ‘Collaboration on science and innovation: A FUTURE PARTNERSHIP PAPER’

Government Publishes paper on ‘Collaboration on science and innovation: A FUTURE PARTNERSHIP PAPER’ The United Kingdom wants to build a new, deep and special partnership with the European Union. This paper is part of a series setting out key issues which form part of the Government’s vision for that partnership, and which will explore how the UK and the EU, working together,

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CBMNet awarded – Industrial Biotechnology Catalyst Seeding Funding

CBMNet awarded Industrial Strategy Challenge Funding We are pleased to announce that CBMNet has been awarded £150,000 from the Industrial Strategy Challenge Fund in the form of an Industrial Biotechnology Catalyst Seeding Award.   £100,000 of this has just been awarded to Dr Alan Goddard, Aston University, in the form of a CBMNet FLAGSHIP award – Consolidation, Integration and Critical Mass

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Information Days on 2018-2020 Horizon 2020 Calls for Proposals

Information Days on 2018-2020 Horizon 2020 Calls for Proposals The European Commission will organise a number of information days in Brussels on the upcoming 2018-2020 calls for proposals in the last Work Programme of Horizon 2020 (to be published in October). These events will provide information on the content of the calls and will often be combined with dedicated brokerage

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Synthetic Biology Start-up company survey results

Synthetic Biology Start-up company survey results A survey of synthetic biology company start-ups in the UK is published today by SynbiCITE, the UK’s national centre for the commercialisation of synthetic biology. The study reveals a vibrant ecosystem sustaining a thriving and rapidly growing sector of the bioeconomy. Highlighting sources of innovation and entrepreneurship, and exploring R&D, technology transfer, investment and growth,

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SPOTLIGHT ON INDUSTRY: Keith Thomas, Brewlab Limited

Keith Thomas, Brewlab Limited What is your background and current job role? Brewlab is a leading provider of training and analysis services for the international brewing industry, based in purpose built premises on the banks of the river Wear in Sunderland. I am currently director of Brewlab Ltd, responsible for company developments and project management.  I am also a senior

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SPOTLIGHT ON INDUSTRY: Charles Bavington, GlycoMar

Charles Bavington, GlycoMar What is your background and current job role? I am the founder of GlycoMar and a biochemist with over 15 years experience in marine biotechnology. I graduated of the University of Edinburgh and then completed my PhD at the same university, studying proteoglycan metabolism in cartilage. This was followed by postdoctoral research at Dunstaffnage marine lab studying invertebrate

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Biosynthesis of the antibiotic nonribosomal peptide penicillin in baker’s yeast

Biosynthesis of the antibiotic nonribosomal peptide penicillin in baker’s yeast Fungi are a valuable source of enzymatic diversity and therapeutic natural products including antibiotics. Here we engineer the baker’s yeast Saccharomyces cerevisiae to produce and secrete the antibiotic penicillin, a beta-lactam nonribosomal peptide, by taking genes from a filamentous fungus and directing their efficient expression and subcellular localization. Using synthetic

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Whole-cell biocatalysts by design

Whole-cell biocatalysts by design Whole-cell biocatalysts provide unique advantages and have been widely used for the efficient biosynthesis of value-added fine and bulk chemicals, as well as pharmaceutically active ingredients. What is more, advances in synthetic biology and metabolic engineering, together with the rapid development of molecular genetic tools, have brought about a renaissance of whole-cell biocatalysis. These rapid advancements

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