CBMNet awarded ISCF Industrial Biotechnology Catalyst Early Stage Feasibility Projects

CBMNet awarded ISCF Industrial Biotechnology Catalyst Early Stage Feasibility Projects We are pleased to confirm that UK Research and Innovation (UKRI), the Biotechnology and Biological Science Research Council (BBSRC)  has agreed to provide a grant of £233,222 to the CBMNet to support Industrial Biotechnology Catalyst: Early Stage Feasibility Projects, provided through Wave 1 of the Industrial Strategy Challenge Fund (ISCF).

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Converting Escherichia coli into an archaebacterium with a hybrid heterochiral membrane Antonella Caforio, Melvin F. Siliakus, Marten Exterkate, Samta Jain, Varsha R. Jumde, Ruben L. H. Andringa, Servé W. M. Kengen, Adriaan J. Minnaard, Arnold J. M. Driessen and John van der OostPNAS April 3, 2018. 115 (14) 3704-3709; published ahead of print March 19, 2018. https://doi.org/10.1073/pnas.1721604115 Significance Escherichia coli has been engineered toward an archaebacterium with an unprecedented high level of archaeal ether phospholipids. The obtained cells stably

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CBMNet and IBCarb awarded BBSRC International Workshop Award

CBMNet and IBCarb awarded BBSRC International Workshop Award BBSRC has identified industrial biotechnology and bioenergy as high-level priority areas in its Delivery Plan for 2016-2020. Supporting the BBSRC to achieve its strategic goals, this focussed workshop will identify the science and technological barriers that need to be addressed in order to harness the potential of plant ‘cell factories’ for producing biopharmaceuticals. A CBMNet-driven symposium

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Translation Stress Positively Regulates MscL-Dependent Excretion of Cytoplasmic Proteins

Translation Stress Positively Regulates MscL-Dependent Excretion of Cytoplasmic Proteins ABSTRACT The apparent mislocalization or excretion of cytoplasmic proteins is a commonly observed phenomenon in both bacteria and eukaryotes. However, reports on the mechanistic basis and the cellular function of this so-called “nonclassical protein secretion” are limited. Here we report that protein overexpression in recombinant cells and antibiotic-induced translation stress in

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€2.4M European ERA CoBioTech Project Success for CBMNet

€2.4M European ERA CoBioTech Project Success for CBMNet   We are proud to announce that a CBMNet led proposal to the First transnational Call for research projects within the framework of the ERA-NET Cofund on Biotechnologies (ERA CoBioTech) “Biotechnology for a Sustainable Bioeconomy”, has been successful. Developed through CBMNet and led by CBMNet Management Board member Dr Alan Goddard, with CBMNet Co-Director

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CBMNet IN-FOCUS 2016-2017: Our Network’s Impact

CBMNet IN-FOCUS 2016-2017: Our Network’s Impact **Download IN-FOCUS here.** A welcome from Professor Jeff Green, CBMNet Director…… Welcome to the latest issue of IN-FOCUS. Since its launch in 2014 CBMNet has worked to build an international community of academics and industrial biotechnology practitioners to raise awareness of the importance of membrane function, and in particular the transport of substrates and products, in creating efficient bioprocesses.

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SPOTLIGHT ON INDUSTRY: Dr Tithira Wimalasena, Senior Fermentation Scientist, Calysta

   Dr Tithira Wimalasena, Senior Fermentation Scientist, Calysta What is your background and current job role? After graduating with a BSc in Microbiology, I obtained a Masters in Applied Molecular Microbiology from University of Nottingham. Following this I completed a PhD at the same university, understanding the unfolded protein response of Candida albicans which was related to Medical Microbiology.  On

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